Comparison of Total Phenolic Content and Antioxidant Activity of Indonesian Propolis Extracted with Various Solvents.

Propolis is a widely used medicine that may be found in both its pure form and when combined with othernatural ingredients over-the-counter preparations, cosmetics, health foods. Some customers develop alcohol sensitivity after using ethanol, which common solvent to extract propolis. As propolis solvents, various Natural Deep Eutectic Solvents (NaDES) were examined this study. Choline chloride, propylene glycol, glycerol, citric acid, 1,2-propanediol molar ratios create some of the NaDES employed. solvents kinetic maceration ratio for extraction process. The Folin-Ciocalteu method was measure total phenolic content (TPC), DPPH assay antioxidant activity. In ethanol TPC ranged from 136.52 ± 27.9 365.8 20.54 mgGAE/g. values activity 45.94 183.76 ppm. lowest IC50 highest choline chloride-glycerol (CCG). It discovered optimum extracting CCG-based. potential use Indonesian propolis, as an medium formulation element.